METTL3 activator-1 (free base)
METTL3 activator-1 free base (compound 4) is a potent METTL3/METTL14/WTAP activator. METTL3 activator-1 free base increases HIV-1 p24 virion production. METTL3 activator-1 free base increases the N6-adenosine methylation level in the viral RNA genome[1].
Product Specifications
CAS Number
[2758-98-7]
UNSPSC
12352005
Hazard Statement
H302-H319
Target
HIV; METTL3
Related Pathways
Anti-infection; Epigenetics
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
COC(=O)C1CNCCN1
Molecular Formula
C6H12N2O2
Molecular Weight
144.17
Precautions
P264-P270-P280-P330-P501
References & Citations
[1]Selberg S, et al. HIV Replication Is Increased by RNA Methylation METTL3/METTL14/WTAP Complex Activators. ACS Omega. 2021 Jun 11;6 (24) :15957-15963.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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