Geranic acid

Geranic acid is a monoterpenemainly used in flavor, fragrance, cosmetics and agro-industries[1]. In vitro studies show that geranic acid exhibits strong inhibitory activity against Fusarium graminearum and Colletotrichum graminicola, the two main fungal pathogens of maize[2]. It also exhibits antitumor activity[3].

Product Specifications

CAS Number

[459-80-3]

Product Name Alternative

Geranate; NSC 229335; GAGE

UNSPSC

12352211

Hazard Statement

H312, H315, H317

Target

Fungal

Related Pathways

Anti-infection

Field of Research

Cancer; Infection

Purity

90.0

Smiles

C/C(C)=C/CC/C(C)=C/C(O)=O

Molecular Formula

C10H16O2

Molecular Weight

168.23

Precautions

H312, H315, H317

References & Citations

[1]Di Mola, Antonia; Massa, Antonio; De Feo, Vincenzo; Basile, Anna; Pascale, Maria; Aquino, Rita Patrizia; De Caprariis, Paolo (2017) . Effect of citral and citral related compounds on viability of pancreatic and human B-lymphoma cell lines. Medicinal Chemistry Research, 26 (3), 631–639.|[2]Yang T, Stoopen G, Yalpani N, Vervoort J, de Vos R, Voster A, Verstappen FW, Bouwmeester HJ, Jongsma MA. Metabolic engineering of geranic acid in maize to achieve fungal resistance is compromised by novel glycosylation patterns. Metab Eng. 2011 Jul;13 (4) :414-25. |[3]Mi J, Becher D, Lubuta P, Dany S, Tusch K, Schewe H, Buchhaupt M, Schrader J. De novo production of the monoterpenoid geranic acid by metabolically engineered Pseudomonas putida. Microb Cell Fact. 2014 Dec 4;13:170.