DMA4-H228

DMA4-H228 is a highly spleen-targeted, ionizable cationic liposome. DMA4-H228 is used to prepare lipid nanoparticles (LNPs) loaded with mRNA for the delivery of mRNA in vivo[1].

Product Specifications

CAS Number

[3091917-64-2]

UNSPSC

12352005

Target

Liposome

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer; Inflammation/Immunology

Smiles

O=C(CCC(N(CCCCCCCC)CCCCCCCC)=O)OCCOC(CCN(CCC1N(CCC1)C)CCC(OCCOC(CCC(N(CCCCCCCC)CCCCCCCC)=O)=O)=O)=O

Molecular Formula

C57H106N4O10

Molecular Weight

1007.47

References & Citations

[1]Liang X, et al. Dimethylamino-based synthetic lipidoid nanoparticles for selective mRNA delivery to splenic antigen-presenting cells. J Control Release. 2025 Jun 10;382:113737.