DMA4-H228
DMA4-H228 is a highly spleen-targeted, ionizable cationic liposome. DMA4-H228 is used to prepare lipid nanoparticles (LNPs) loaded with mRNA for the delivery of mRNA in vivo[1].
Product Specifications
CAS Number
3091917-64-2
UNSPSC
12352005
Target
Liposome
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C(CCC(N(CCCCCCCC)CCCCCCCC)=O)OCCOC(CCN(CCC1N(CCC1)C)CCC(OCCOC(CCC(N(CCCCCCCC)CCCCCCCC)=O)=O)=O)=O
Molecular Formula
C57H106N4O10
Molecular Weight
1007.47
References & Citations
[1]Liang X, et al. Dimethylamino-based synthetic lipidoid nanoparticles for selective mRNA delivery to splenic antigen-presenting cells. J Control Release. 2025 Jun 10;382:113737.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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