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4A3-SC10

4A3-SC10 is an ionizable cationic lipid (pKa = 6.57) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA. 4A3-SC10 can be used for drug delivery in cancer[1].

Product Specifications

CAS Number

[1857340-80-7]

UNSPSC

12352211

Target

Others

Related Pathways

Others

Field of Research

Cancer

Smiles

CCCCCCCCCCSCC(C(OCCOC(CCN(CCCN(CCCN(CCC(OCCOC(C(CSCCCCCCCCCC)C)=O)=O)CCC(OCCOC(C(CSCCCCCCCCCC)C)=O)=O)C)CCC(OCCOC(C(CSCCCCCCCCCC)C)=O)=O)=O)=O)C

Molecular Formula

C83H155N3O16S4

Molecular Weight

1579.39

References & Citations

[1]Chen Z, et al. Modular Design of Biodegradable Ionizable Lipids for Improved mRNA Delivery and Precise Cancer Metastasis Delineation In Vivo. J Am Chem Soc. 2023 Nov 8;145 (44) :24302-24314.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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