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Thalidomide-O-amido-PEG2-Mal

Thalidomide-O-amido-PEG2-Mal is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-O-amido-PEG2-Mal can be linked to a target protein ligand via a linker to form a PROTAC.

Product Specifications

UNSPSC

12352005

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C(NCCOCCOCCN1C(C=CC1=O)=O)COC2=C3C(N(C(C3=CC=C2)=O)C4CCC(NC4=O)=O)=O

Molecular Formula

C25H26N4O10

Molecular Weight

542.49

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

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