Bis-PEG2-amine-Thalidomide (hydrochloride)
Bis-PEG2-amine-Thalidomide hydrochloride is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Bis-PEG2-amine-Thalidomide hydrochloride can be linked to a target protein ligand via a linker to form a PROTAC.
Product Specifications
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
NCCOCCOCCOC1=C2C(N(C(C2=CC=C1)=O)C3CCC(N(C3=O)CCOCCOCCN)=O)=O.Cl
Molecular Formula
C25H37ClN4O9
Molecular Weight
573.04
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Frequently Asked Questions
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