Thalidomide-Piperazine-PEG2-NH2 (hydrochloride)
Thalidomide-Piperazine-PEG2-NH2 hydrochloride is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-Piperazine-PEG2-NH2 hydrochloride can be linked to a target protein ligand via a linker to form a PROTAC.
Product Specifications
CAS Number
[2357110-15-5]
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
Cl.O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)N4CCN(CCOCCOCCN)CC4
Molecular Formula
C23H32ClN5O6
Molecular Weight
509.99
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
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