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Thalidomide-Piperazine-PEG2-NH2 (hydrochloride)

Thalidomide-Piperazine-PEG2-NH2 hydrochloride is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-Piperazine-PEG2-NH2 hydrochloride can be linked to a target protein ligand via a linker to form a PROTAC.

Product Specifications

CAS Number

[2357110-15-5]

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

Cl.O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)N4CCN(CCOCCOCCN)CC4

Molecular Formula

C23H32ClN5O6

Molecular Weight

509.99

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Curated Selection

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