Thalidomide-O-amido-PEG1-azide
Thalidomide-O-amido-PEG1-azide is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-O-amido-PEG1-azide can be linked to a target protein ligand via a linker to form a PROTAC.
Product Specifications
CAS Number
[2597167-25-2]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
[N-]=[N+]=NCCOCCNC(=O)COC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
Molecular Formula
C19H20N6O7
Molecular Weight
444.40
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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