Thalidomide-O-PNB ester
Thalidomide-O-PNB ester is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-O-PNB ester can be linked to a target protein ligand via a linker to form a PROTAC.
Product Specifications
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C1CCC(C(N1)=O)N2C(C3=C(C(OCC(OC4=CC=C([N+]([O-])=O)C=C4)=O)=CC=C3)C2=O)=O
Molecular Formula
C21H15N3O9
Molecular Weight
453.36
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Frequently Asked Questions
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