Antifungal agent 136
Antifungal agent 136 (Compound M-15) is an irreversible fungal lanosterol 14α-demethylase (CYP51) inhibitor. Antifungal agent 136 exhibits potent antifungal activity against drug-resistant Candida albicans and downregulates IL-6 expression. Antifungal agent 136 is promising for research of fungal infection and inflammatory disease[1].
Product Specifications
CAS Number
[3075607-57-4]
UNSPSC
12352005
Target
Cytochrome P450; Fungal; Interleukin Related
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Infection; Inflammation/Immunology
Concentration
10mM
Purity
99.60
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@@H](SSCCCC1=CC=NC=C1)[C@@](O)(C2=C(C=C(C=C2)F)F)CN3C=NC=N3
Molecular Formula
C20H22F2N4OS2
Molecular Weight
436.54
References & Citations
[1]Sun ZK, et al. Antifungal compounds, preparation methods and uses thereof. CN119431313A. 2025-02-14.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
CYP51
Available Sizes
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