BDPI

BDPI is the a BODIPY derivative. BDPI reveals a high O2 quantum yield and exhibits phototoxicity that inhibits HeLa with an IC50 of 0.6 µg/mL. BDPI nanoarticles can be taken up by HeLa, producing fluorescence signals in the cells, and can be used as cell imaging agent. BDPI nanoarticles exhibit antitumor efficacy in mouse models[1].

Product Specifications

CAS Number

1083009-44-2

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Fluorescent Dye; Reactive Oxygen Species (ROS)

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Cancer

Purity

98.10

Smiles

CC(C(I)=C1C)=C(N1[B-]2(F)F)C(C3=CC=CC=C3)=C4[N+]2=C(C)C(I)=C4C

Molecular Formula

C19H17BF2I2N2

Molecular Weight

575.97

Precautions

H302, H315, H319, H335

References & Citations

[1]Zou J, et al., BODIPY Derivatives for Photodynamic Therapy: Influence of Configuration versus Heavy Atom Effect. ACS Appl Mater Interfaces. 2017 Sep 27;9 (38) :32475-32481.