5’- (E) -VPG Phosphoramidite
5'- (E) -VPG Phosphoramidite (5' (E) -VP-2'-OMe-iBu-GPhosphoramidite) is a structurally modified phosphoramidite reagent used to synthesize biologically stable oligonucleotides. 5'- (E) -VPG Phosphoramidite (POM) carries a VP protecting group and can be coupled to the target oligonucleotide at the 5' end via solid-phase synthesis. The modified oligonucleotide is then constructed through oxidation and deprotection steps. 5'- (E) -VPG Phosphoramidite is suitable for RNAi and viral replication research[1].
Product Specifications
Product Name Alternative
5' (E) -VP-2'-OMe-iBu-G Phosphoramidite
UNSPSC
12352005
Target
DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Infection
Smiles
CC(C)N(C(C)C)P(O[C@H]1[C@@H](OC)[C@H](N2C(N=C(NC(C(C)C)=O)NC3=O)=C3N=C2)O[C@@H]1/C=C/P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)OCCC#N
Molecular Formula
C37H59N7O13P2
Molecular Weight
871.85
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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