3- (5-Bromo-2-chlorophenyl) piperidine-2,6-dione

3- (5-Bromo-2-chlorophenyl) piperidine-2,6-dione is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC.

Product Specifications

CAS Number

[2990057-63-9]

UNSPSC

12352005

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C(C(C1=CC(Br)=CC=C1Cl)CC2)NC2=O

Molecular Formula

C11H9BrClNO2

Molecular Weight

302.55

References & Citations

[1]Miletić N, et al. Workflow for E3 Ligase Ligand Validation for PROTAC Development. ACS Chem Biol. 2025 Feb 21;20 (2) :507-521.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Curated Selection

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