3,3'- (Propane-2,2-diylbis (sulfanediyl) ) dipropionic acid
3,3'- (Propane-2, 2-Diylbis (sulfanediyl) ) dipropionic acid is a ROS-sensitive cleavable linker that can be used in the synthesis of ADCs. 3,3'- (Propane-2,2-diylbis (sulfanediyl) ) dipropionic acid is promising for research of tumor drug delivery systems[1].
Product Specifications
CAS Number
[4265-59-2]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
97.0
Smiles
CC(SCCC(O)=O)(SCCC(O)=O)C
Molecular Formula
C9H16O4S2
Molecular Weight
252.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Xu L , et al. A reactive oxygen species-responsive prodrug micelle with efficient cellular uptake and excellent bioavailability. J Mater Chem B. 2018 Feb 21;6 (7) :1076-1084.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
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