3,3'- (Propane-2,2-diylbis (sulfanediyl) ) dipropionic acid

3,3'- (Propane-2, 2-Diylbis (sulfanediyl) ) dipropionic acid is a ROS-sensitive cleavable linker that can be used in the synthesis of ADCs. 3,3'- (Propane-2,2-diylbis (sulfanediyl) ) dipropionic acid is promising for research of tumor drug delivery systems[1].

Product Specifications

CAS Number

[4265-59-2]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

97.0

Smiles

CC(SCCC(O)=O)(SCCC(O)=O)C

Molecular Formula

C9H16O4S2

Molecular Weight

252.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Xu L , et al. A reactive oxygen species-responsive prodrug micelle with efficient cellular uptake and excellent bioavailability. J Mater Chem B. 2018 Feb 21;6 (7) :1076-1084.