Myristoyl tetrapeptide-12

Myristoyl tetrapeptide-12 directly activates SMAD2 and induces the linking of SMAD3 with DNA. Myristoyl tetrapeptide-12 is capable of stimulating hair growth, especially at the level of eyelashes[1][2].

Product Specifications

CAS Number

[959610-24-3]

UNSPSC

12352209

Hazard Statement

H302-H315-H319-H335

Target

TGF-beta/Smad

Related Pathways

Stem Cell/Wnt; TGF-beta/Smad

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Solubility

10 mM in DMSO

Smiles

C[C@@H](C(N)=O)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCCCN)NC(CCCCCCCCCCCCC)=O)=O)=O)=O

Molecular Formula

C32H63N7O5

Molecular Weight

625.89

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Haeyoung Kwon, et al. Smad-induced alterations of matrix metabolism by a myristoyl tetra peptide. Cell Biochem Funct. 2014 Dec;32 (8) :665-74.|[2]C. Diehl. Peptides in cosmeceuticals. ISSN 1727-5741 (Print), ISSN 2522-1035 (Online) .