Hsp90-IN-37
Hsp90-IN-37 (Z-2) is a heat shock protein 90 (Hsp90) inhibitor that inhibits Hsp90 enzymatic activity by 69%. Hsp90-IN-37 has antitumor activity[1].
Product Specifications
CAS Number
[1383133-23-0]
UNSPSC
12352005
Hazard Statement
H315, H317, H319, H335
Target
HSP
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Field of Research
Cancer
Purity
97.0
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(N1C(N)=NC2=CC=CC=C12)OC(C)(C)C
Molecular Formula
C12H15N3O2
Molecular Weight
233.27
Precautions
H315, H317, H319, H335
References & Citations
[1]Abbasi M, et al. Identification of New Hsp90 Inhibitors: Structure Based Virtual Screening, Molecular Dynamic Simulation, Synthesis and Biological Evaluation. Anticancer Agents Med Chem. 2021;21 (18) :2583-2591.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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