EDTA (tetrasodium tetrahydrate)

EDTA tetrasodium tetrahydrate is a metal chelator (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. EDTA tetrasodium tetrahydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. EDTA tetrasodium tetrahydrate can also decrease the formation of disulfide bonds[1][2][3].

Product Specifications

CAS Number

[13235-36-4]

Product Name Alternative

Ethylenediaminetetraacetic acid (tetrasodium tetrahydrate)

UNSPSC

12352200

Hazard Statement

H302+H332, H318, H373

Target

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Purity

97.0

Solubility

10 mM in DMSO

Smiles

O=C(O[Na])CN(CC(O[Na])=O)CCN(CC(O[Na])=O)CC(O[Na])=O.O.O.O.O

Molecular Formula

C10H20N2Na4O12

Molecular Weight

452.23

Precautions

H302+H332, H318, H373

References & Citations

[1]Chumanov RS, et al. Artifact-inducing enrichment of ethylenediaminetetraacetic acid and ethyleneglycoltetraacetic acid on anion exchange resins. Anal Biochem. 2011 May 1;412 (1) :34-9.|[2]Banfi G, et al. The role of ethylenediamine tetraacetic acid (EDTA) as in vitro anticoagulant for diagnostic purposes. Clin Chem Lab Med. 2007;45 (5) :565-76.|[3]Ibad A, et al. Chelation therapy in the treatment of cardiovascular diseases. J Clin Lipidol. 2016 Jan-Feb;10 (1) :58-62.