Vasorelaxant agent-2
Vasorelaxant agent-2 (Compound 8h) targets α1A-adrenergic receptor with an affinity of pD2=5.4. Vasorelaxant agent-2 exhibits vasodilator activity in rats aortic rings with an EC50 of 0.79 μM[1].
Product Specifications
CAS Number
[53242-88-9]
UNSPSC
12352005
Hazard Statement
H302-H312-H315-H319-H332-H335
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Cardiovascular Disease
Smiles
O=C1NN=C(CC2=CC=C(Cl)C=C2)C3=C1C=CC=C3
Molecular Formula
C15H11ClN2O
Molecular Weight
270.71
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]del Olmo E, et al., Vasorelaxant activity of phthalazinones and related compounds. Bioorg Med Chem Lett. 2006 May 15;16 (10) :2786-90.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W103372/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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