1,2-Benzisoxazole

1,2-Benzisoxazole (Indoxazene) is a potential substrate of rabbit liver aldehyde oxidase. 1,2-Benzisoxazole was used in the discovery and development of zonisamide (HY-B0124) for the study of epilepsy and Parkinson's disease[1].

Product Specifications

CAS Number

[271-95-4]

Product Name Alternative

Indoxazene

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Drug Intermediate

Related Pathways

Others

Field of Research

Neurological Disease

Purity

97.0

Smiles

C1=CC=C2C(=C1)C=NO2

Molecular Formula

C7H5NO

Molecular Weight

119.12

Precautions

H315, H319, H335

References & Citations

[1]Uto Y. 1, 2-Benzisoxazole: A Privileged Structure with a Potential for Polypharmacology. Curr Pharm Des. 2016;22 (21) :3201-11. |[2]Gristwood W, et al. Kinetics of some benzothiazoles, benzoxazoles, and quinolines as substrates and inhibitors of rabbit liver aldehyde oxidase. Xenobiotica. 1988 Aug;18 (8) :949-54.