SKF-102698
SKF-102698 is a dopamine β-hydroxylase inhibitor. SKF 102698 increases endogenous dopamine levels. SKF-102698 can be used in hypertension research[1][2].
Product Specifications
CAS Number
95333-81-6
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Dopamine β-hydroxylase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
FC=1C=C(F)C=C(C1)CN2C=CNC2=S
Molecular Formula
C10H8F2N2S
Molecular Weight
226.25
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Dey SK, et al. Dopamine β hydroxylase as a potential drug target to combat hypertension. Expert Opin Investig Drugs. 2020 Sep;29 (9) :1043-1057.|[2]Bates MD, et al. Desensitization of DA1 dopamine receptors coupled to adenylyl cyclase in opossum kidney cells. Am J Physiol. 1991 Jun;260 (6 Pt 2) :F937-45.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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