SKF-102698

SKF-102698 is a dopamine β-hydroxylase inhibitor. SKF 102698 increases endogenous dopamine levels. SKF-102698 can be used in hypertension research[1][2].

Product Specifications

CAS Number

[95333-81-6]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Dopamine β-hydroxylase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Smiles

FC=1C=C(F)C=C(C1)CN2C=CNC2=S

Molecular Formula

C10H8F2N2S

Molecular Weight

226.25

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Dey SK, et al. Dopamine β hydroxylase as a potential drug target to combat hypertension. Expert Opin Investig Drugs. 2020 Sep;29 (9) :1043-1057.|[2]Bates MD, et al. Desensitization of DA1 dopamine receptors coupled to adenylyl cyclase in opossum kidney cells. Am J Physiol. 1991 Jun;260 (6 Pt 2) :F937-45.