8,9-Z-Abamectin B1a

8,9-Z-Abamectin B1a is the 8,9-Z-isomer of Abamectin B1a (HY-15308) . Avermectin B1a is an antiparasitic agent that paralyzes nematodes[1][2].

Product Specifications

CAS Number

[113665-89-7]

UNSPSC

12352005

Target

Drug Isomer; Parasite

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

O=C1OC(C[C@@]2(O[C@H]([C@@H](C)CC)[C@@H](C)C=C2)O3)C[C@H]3C/C=C(C)/[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)C(O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)/C=C/C=C6[C@]7(O)[C@H]1C=C(C)[C@@H](O)C7OC/6

Molecular Formula

C48H72O14

Molecular Weight

873.08

References & Citations

[1]Sun Y, et al. Bioaccumulation and elimination of avermectin B1a in the earthworms (Eisenia fetida) . Chemosphere. 2005 Jul;60 (5) :699-704.|[2]Payne GT, et al. Activation of gamma-aminobutyric acid insensitive chloride channels in mouse brain synaptic vesicles by avermectin B1a. J Biochem Toxicol. 1991 Winter;6 (4) :283-92.