Trimethylbenzoquinone
Trimethylbenzoquinone (Compound 5) is a methylated benzoquinone. Trimethylbenzoquinone exhibits moderate cytotoxicity against K562 cells, with its IC50 being 0.75 μM. Trimethylbenzoquinone is completely unable to cause inter-strand DNA cross-linking and cannot alkylate DNA guanines. Trimethylbenzoquinone can be used to study the relationship between the nitrogen heterocyclic group and DNA cross-linking[1].
Product Specifications
CAS Number
[935-92-2]
UNSPSC
12352211
Hazard Statement
H301+H311, H315, H319
Target
Others
Related Pathways
Others
Field of Research
Cancer
Purity
99.87
Smiles
O=C1C=C(C(=O)C(=C1C)C)C
Molecular Formula
C9H10O2
Molecular Weight
150.18
Precautions
H301+H311, H315, H319
References & Citations
[1]Mayalarp SP, et al. Cross-linking and sequence specific alkylation of DNA BY aziridinylquinones. 1. Quinone methides. J Med Chem. 1996 Jan 19;39 (2) :531-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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