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(S) -E3 ligase Ligand 42

(S) -E3 ligase Ligand 42 is a ligand for E3 ubiquitin ligase. (S) -E3 ligase Ligand 42 can be connected to the ligand for protein by a linker to form GDC-2992 (HY-156751A) . PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

Product Specifications

UNSPSC

12352005

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C([C@@H](N(N=CC1=C2C=CC(F)=C1)C2=O)CC3)NC3=O

Molecular Formula

C13H10FN3O3

Molecular Weight

275.24

References & Citations

[1]HF Lu, et al. Phthalazinone compound, and preparation method therefor and medical use thereof. WO2021249534A1. 2021-12-16.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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