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4-Chloro-7-ethoxyquinoline

4-Chloro-7-ethoxyquinoline (Compound 9a), a quinolone derivative, is an anticancer agent. 4-Chloro-7-ethoxyquinoline can inhibit proliferation of HCT-116, RKO, DLD1, HepG2, BGC-823, NCI-H1650 and SK-OV-3 cells with IC50 values of 3.16, 3.87, 2.75, 2.66, 3.91, 3.34 and 3.46μM[1].

Product Specifications

CAS Number

178984-50-4

UNSPSC

12352005

Hazard Statement

H302-H315-H318-H335

Target

Drug Derivative

Related Pathways

Others

Field of Research

Cancer

Smiles

ClC=1C=CN=C2C=C(OCC)C=CC12

Molecular Formula

C11H10ClNO

Molecular Weight

207.66

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Li S, et al. Design, synthesis, structure-activity relationships and mechanism of action of new quinoline derivatives as potential antitumor agents. Eur J Med Chem. 2019 Jan 15;162:666-678.

Shipping Conditions

Room temperature

Scientific Category

Reference compound2

Clinical Information

No Development Reported

Frequently Asked Questions

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