4-Chloro-7-ethoxyquinoline
4-Chloro-7-ethoxyquinoline (Compound 9a), a quinolone derivative, is an anticancer agent. 4-Chloro-7-ethoxyquinoline can inhibit proliferation of HCT-116, RKO, DLD1, HepG2, BGC-823, NCI-H1650 and SK-OV-3 cells with IC50 values of 3.16, 3.87, 2.75, 2.66, 3.91, 3.34 and 3.46μM[1].
Product Specifications
CAS Number
178984-50-4
UNSPSC
12352005
Hazard Statement
H302-H315-H318-H335
Target
Drug Derivative
Related Pathways
Others
Field of Research
Cancer
Smiles
ClC=1C=CN=C2C=C(OCC)C=CC12
Molecular Formula
C11H10ClNO
Molecular Weight
207.66
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Li S, et al. Design, synthesis, structure-activity relationships and mechanism of action of new quinoline derivatives as potential antitumor agents. Eur J Med Chem. 2019 Jan 15;162:666-678.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported
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