3-Desmethyl Gatifloxacin

3-Desmethyl Gatifloxacin (8-Methoxy Ciprofloxacin) induces DNA cleavage mediated by wild-type gyrase and Quinolone-resistant mutants. 3-Desmethyl Gatifloxacin can be used for research of drug resistance[1].

Product Specifications

CAS Number

[112811-57-1]

Product Name Alternative

8-Methoxy Ciprofloxacin; 8-Methoxy-cipro

UNSPSC

12352005

Hazard Statement

H302+H312+H332

Target

Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

O=C(C1=CN(C2CC2)C3=C(C(N4CCNCC4)=C(C=C3C1=O)F)OC)O

Molecular Formula

C18H20FN3O4

Molecular Weight

361.37

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

References & Citations

[1]Ashley RE, et al. Interactions between Quinolones and Bacillus anthracis Gyrase and the Basis of Drug Resistance. Biochemistry. 2017 Aug 15;56 (32) :4191-4200.