2,4-Dinitrobenzenesulfonic acid
2,4-Dinitrobenzenesulfonic acid (Compound 3) is a ecto-5'-Nucleotidase (CD73) inhibitor with a Ki value of 63 μM for human and 144 μM for rat. 2,4-Dinitrobenzenesulfonic acid can inhibit the hydrolysis of adenosine monophosphate (AMP) to generate adenosine. 2,4-Dinitrobenzenesulfonic acid can be used for the research of cancer[1].
Product Specifications
CAS Number
[89-02-1]
UNSPSC
12352005
Hazard Statement
H314, H315, H318, H319
Target
CD73
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Purity
99.81
Smiles
O=S(C(C([N+]([O-])=O)=C1)=CC=C1[N+]([O-])=O)(O)=O
Molecular Formula
C6H4N2O7S
Molecular Weight
248.17
Precautions
H314, H315, H318, H319
References & Citations
[1]Raza R, et al. Identification of small molecule sulfonic acids as ecto-5'-Nucleotidase inhibitors. Med Chem. 2012 Nov;8 (6) :1133-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
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