Thalidomide-4-OH- (S) -CH3
Thalidomide-4-OH- (S) -CH3 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-4-OH- (S) -CH3 can be linked to a target protein ligand via a linker to form a PROTAC.
Product Specifications
CAS Number
[1957235-70-9]
UNSPSC
12352005
Hazard Statement
H302-H361-H373
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
C[C@@]1(N2C(=O)C=3C(C2=O)=CC=CC3O)C(=O)NC(=O)CC1
Molecular Formula
C14H12N2O5
Molecular Weight
288.26
Precautions
P264-P270-P280-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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