P-Hydroxyphenylacetone

P-Hydroxyphenylacetone, a Raspberry ketone (HY-N1426) derivative, is an androgen receptor (AR) antagonist with an IC50 of 420 μM in MDA-kb2 human breast cancer cells. p-Hydroxyphenylacetone can be used for breast cancer research[1].

Product Specifications

CAS Number

[770-39-8]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Androgen Receptor

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Smiles

O=C(CC1=CC=C(C=C1)O)C

Molecular Formula

C9H10O2

Molecular Weight

150.17

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Ogawa Y, et al. Effect of essential oils, such as raspberry ketone and its derivatives, on antiandrogenic activity based on in vitro reporter gene assay. Bioorg Med Chem Lett. 2010 Apr 1;20 (7) :2111-4.