EPHA4 antagonist-1
EPHA4 antagonist-1 (Compound 2) is an EphA4 receptor antagonist. EPHA4 antagonist-1 is also an EphA2 receptor antagonist. EPHA4 antagonist-1 inhibits ephrin-A5 AP binding to EphA4 Fc receptor, with an IC50 of 10 μM[1].
Product Specifications
CAS Number
[313701-92-7]
UNSPSC
12352005
Hazard Statement
H315-H317-H318
Target
Ephrin Receptor
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(C1=CC(N2C(C)=CC=C2C)=CC=C1O)O
Molecular Formula
C13H13NO3
Molecular Weight
231.25
Precautions
P261-P264-P272-P280-P302+P352-P362+P364-P501
References & Citations
[1]Noberini R, et al. A disalicylic acid-furanyl derivative inhibits ephrin binding to a subset of Eph receptors. Chem Biol Drug Des. 2011 Oct;78 (4) :667-78.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
EphA
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
304863-01 50 µL
ADCY 1 (ADCY1, Adenylate cyclase type 1, ATP pyrophosphate-lyase 1, Adenylate cyclase type I, Adenylyl cyclase 1, Ca (2+) /calmodulin-activated adenylyl cyclase)
Ask
View Details 304863-02 100 µL
ADCY 1 (ADCY1, Adenylate cyclase type 1, ATP pyrophosphate-lyase 1, Adenylate cyclase type I, Adenylyl cyclase 1, Ca (2+) /calmodulin-activated adenylyl cyclase)
Ask
View Details F0351 96 Tests
Mitochondrial Peptide methionine sulfoxide Reductase (MSRA) Bovine ELISA Kit
Ask
View Details 