AChE-IN-23-d10

AChE-IN-23-d10 (4-Amino-Alpha-diethyl amino-o-cresol-d10 (dihydrochloride) ) is the deuterium labeled AChE-IN-23 (HY-W077226) . AChE-IN-23 (compound 3h) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 48.3 μM[1].

Product Specifications

Product Name Alternative

4-Amino-Alpha-diethyl amino-o-cresol-d10 (dihydrochloride)

UNSPSC

12352005

Target

Cholinesterase (ChE) ; Isotope-Labeled Compounds

Related Pathways

Neuronal Signaling; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

OC1=C(C=C(C=C1)N)CN(C(C([2H])([2H])[2H])([2H])[2H])C(C([2H])([2H])[2H])([2H])[2H].Cl.Cl

Molecular Formula

C11H10D10Cl2N2O

Molecular Weight

277.26

References & Citations

[1]Martijn Constantijn de Koning, et al. Discovery of a potent non-oxime reactivator of nerve agent inhibited human acetylcholinesterase. Eur J Med Chem. 2018 Sep 5;157:151-160.