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4-Piperidyl N- (2-biphenyl) carbamate

4-Piperidyl N- (2-biphenyl) carbamate (compound MA) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist. 4-Piperidyl N- (2-biphenyl) carbamate exhibits higher affinity for M2 and M3 mAChR than β2AR (M2 pKi = 7.33; M3 pKi = 7.51; β2AR pKi = 4.94) [1].

Product Specifications

CAS Number

171722-92-2

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

MAChR

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Inflammation/Immunology

Purity

99.80

Smiles

O=C(OC1CCNCC1)NC=2C=CC=CC2C=3C=CC=CC3

Molecular Formula

C18H20N2O2

Molecular Weight

296.37

Precautions

H302, H315, H319, H335

References & Citations

[1]Steinfeld T, et al. THRX-198321 is a bifunctional muscarinic receptor antagonist and beta2-adrenoceptor agonist (MABA) that binds in a bimodal and multivalent manner. Mol Pharmacol. 2011 Mar;79 (3) :389-99.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound2

Clinical Information

No Development Reported

Isoform

MAChR2; mAChR3

Available Sizes

Frequently Asked Questions

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