4-Piperidyl N- (2-biphenyl) carbamate
4-Piperidyl N- (2-biphenyl) carbamate (compound MA) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist. 4-Piperidyl N- (2-biphenyl) carbamate exhibits higher affinity for M2 and M3 mAChR than β2AR (M2 pKi = 7.33; M3 pKi = 7.51; β2AR pKi = 4.94) [1].
Product Specifications
CAS Number
[171722-92-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
MAChR
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Inflammation/Immunology
Purity
99.80
Smiles
O=C(OC1CCNCC1)NC=2C=CC=CC2C=3C=CC=CC3
Molecular Formula
C18H20N2O2
Molecular Weight
296.37
Precautions
H302, H315, H319, H335
References & Citations
[1]Steinfeld T, et al. THRX-198321 is a bifunctional muscarinic receptor antagonist and beta2-adrenoceptor agonist (MABA) that binds in a bimodal and multivalent manner. Mol Pharmacol. 2011 Mar;79 (3) :389-99.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
MAChR2; mAChR3
Available Sizes
Curated Selection
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