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3- (4-Hydroxy-1-oxoisoindolin-2-yl) piperidine-2,6-dione (Standard)

Selected Variant

HY-W076696R-01

Size: 10 mg

3- (4-Hydroxy-1-oxoisoindolin-2-yl) piperidine-2,6-dione (Standard) is the analytical standard of 3- (4-Hydroxy-1-oxoisoindolin-2-yl) piperidine-2,6-dione. This product is intended for research and analytical applications. Lenalidomide-4-OH is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-OH can be connected to the ligand for protein by a linker to form PROTAC.

Product Specifications

CAS Number

1061604-41-8

UNSPSC

12352005

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C(C(N(CC1=C2C=CC=C1O)C2=O)CC3)NC3=O

Molecular Formula

C13H12N2O4

Molecular Weight

260.25

References & Citations

[1]Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27 (8) :998-985.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

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