ZIF-8
ZIF-8 (2-Methylimidazole zinc salt) is an anticancer agent that intrinsically induces pyroptosis through a caspase-1/gasdermin D (GSDMD) -dependent pathway[1].
Product Specifications
CAS Number
[59061-53-9]
Product Name Alternative
2-Methylimidazole zinc salt
UNSPSC
12352005
Hazard Statement
H302, H314
Target
Caspase; Pyroptosis
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC1=NC=CN1[Zn]N2C=CN=C2C
Molecular Formula
C8H10N4Zn
Molecular Weight
227.59
Precautions
H302, H314
References & Citations
[1]Ding B, et al. ZIF-8 Nanoparticles Evoke Pyroptosis for High-Efficiency Cancer Immunotherapy. Angew Chem Int Ed Engl. 2023 Mar 1;62 (10) :e202215307.
Shipping Conditions
Room Temperature
Storage Conditions
RT, stored under nitrogen
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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