Palmitoylglycine (Standard)

Palmitoylglycine (Standard) is the analytical standard of Palmitoylglycine. This product is intended for research and analytical applications. Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA[1][2][3].

Product Specifications

CAS Number

[2441-41-0]

Product Name Alternative

N-palmitoyl glycine (Standard)

UNSPSC

12352211

Target

Calcium Channel; NO Synthase; Reference Standards

Related Pathways

Immunology/Inflammation; Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

O=C(O)CNC(CCCCCCCCCCCCCCC)=O

Molecular Formula

C18H35NO3

Molecular Weight

313.48

References & Citations

[1]Neta Rimmerman, et al. N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Mol Pharmacol. 2008 Jul;74 (1) :213-24.|[2]Xu H, et al. N-Palmitoyl glycine activates transient receptor potential channel 5 and increases the risk of Brugada syndrome[J]. medRxiv, 2024: 2024.10. 21.24315897.|[3]Bradshaw HB, et al. Novel endogenous N-acyl glycines identification and characterization. Vitam Horm. 2009;81:191-205.