3-Amino-5- (2-furyl) pyrazole
3-Amino-5- (2-furyl) pyrazole (Compound 14) is a PDK1 binder with an IC50 of 313 μM. 3-Amino-5- (2-furyl) pyrazole can be used in cancer research[1].
Product Specifications
CAS Number
[96799-02-9]
Product Name Alternative
5- (Furan-2-yl) -1H-pyrazol-3-amine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PDK-1
Related Pathways
PI3K/Akt/mTOR
Field of Research
Cancer
Purity
98.0
Smiles
NC1=NNC(C2=CC=CO2)=C1
Molecular Formula
C7H7N3O
Molecular Weight
149.15
Precautions
H302, H315, H319, H335
References & Citations
[1]Medina JR, et al. Aminoindazole PDK1 Inhibitors: A Case Study in Fragment-Based Drug Discovery. ACS Med Chem Lett. 2010 Jul 22;1 (8) :439-42.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
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