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3-Amino-5- (2-furyl) pyrazole

3-Amino-5- (2-furyl) pyrazole (Compound 14) is a PDK1 binder with an IC50 of 313 μM. 3-Amino-5- (2-furyl) pyrazole can be used in cancer research[1].

Product Specifications

CAS Number

[96799-02-9]

Product Name Alternative

5- (Furan-2-yl) -1H-pyrazol-3-amine

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PDK-1

Related Pathways

PI3K/Akt/mTOR

Field of Research

Cancer

Purity

98.0

Smiles

NC1=NNC(C2=CC=CO2)=C1

Molecular Formula

C7H7N3O

Molecular Weight

149.15

Precautions

H302, H315, H319, H335

References & Citations

[1]Medina JR, et al. Aminoindazole PDK1 Inhibitors: A Case Study in Fragment-Based Drug Discovery. ACS Med Chem Lett. 2010 Jul 22;1 (8) :439-42.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound2

Clinical Information

No Development Reported

Curated Selection

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