Antifungal agent 146

Antifungal agent 146 (Compound 19l) is a broad-spectrum antifungal agent. Antifungal agent 146 has inhibitory effects on the main dermatophytes that cause onychomycosis (Trichophyton rubrum, Trichophyton mentagrophytes) and other fungi (Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus) with MIC values of 16, 16, 64, 32, and 32 μg/mL. Antifungal agent 146 can be used for the research of infection[1].

Product Specifications

CAS Number

[174671-88-6]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Fungal

Related Pathways

Anti-infection

Field of Research

Infection

Purity

99.55

Smiles

OB1C2=CC=CC(F)=C2CO1

Molecular Formula

C7H6BFO2

Molecular Weight

151.93

Precautions

H315, H319

References & Citations

[1]Baker S J, et al. Discovery of a new boron-containing antifungal agent, 5-fluoro-1, 3-dihydro-1-hydroxy-2, 1-benzoxaborole (AN2690), for the potential treatment of onychomycosis[J]. Journal of medicinal chemistry, 2006, 49 (15) : 4447-4450.