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1- (Azetidin-3-yl) piperidine

1- (Azetidin-3-yl) piperidine is a PROTAC linker that can be used for synthesis of TQ-3959 (HY-175541) [1].

Product Specifications

CAS Number

[138022-86-3]

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

PROTAC Linkers

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

N1(C2CNC2)CCCCC1

Molecular Formula

C8H16N2

Molecular Weight

140.23

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Ren J, et al. Discovery of TQ-3959 as a Potent and Orally Bioavailable BTK PROTAC Degrader Incorporating a Novel Benzisoxazole-Based CRBN Ligand for the Treatment of B-Cell Malignancies. J Med Chem. 2025 Aug 14;68 (15) :15960-15979.

Shipping Conditions

Room temperature

Scientific Category

Reference compound2

Clinical Information

No Development Reported

Curated Selection

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