Tetrazine-Amine (monohydrochloride)

Tetrazine-Amine monohydrochloride is the monohydrochloride form of Tetrazine-Amine (HY-W053709) . Tetrazine-amine is a Tetrazine linker that can be used to covalently label living cells by cycloaddition[1][2]. Tetrazine-Amine (monohydrochloride) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

Product Specifications

CAS Number

[1416711-59-5]

Product Name Alternative

(4- (1,2,4,5-Tetrazin-3-yl) phenyl) methanamine (monohydrochloride) ; Tetrazine-NH2 (monohydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

99.93

Solubility

DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 70°C) |H2O : ≥ 100 mg/mL

Smiles

NCC1=CC=C(C2=NN=CN=N2)C=C1.Cl

Molecular Formula

C9H10ClN5

Molecular Weight

223.67

Precautions

H302, H315, H319, H335

References & Citations

[1]Devaraj NK, et, al. Fast and sensitive pretargeted labeling of cancer cells through a tetrazine/trans-cyclooctene cycloaddition. Angew Chem Int Ed Engl. 2009;48 (38) :7013-6. |[2]Devaraj NK, et, al. Tetrazine-based cycloadditions: application to pretargeted live cell imaging. Bioconjug Chem. 2008 Dec;19 (12) :2297-9.