Tetrazine-Amine
Tetrazine-Amine ((4- (1,2,4,5-Tetrazin-3-yl) phenyl) methanamine) is a tetrazine linker that can be used to covalently label live cells through a cycloaddition[1][2]. Tetrazine-Amine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
Product Specifications
CAS Number
[1092689-33-2]
Product Name Alternative
(4- (1,2,4,5-Tetrazin-3-yl) phenyl) methanamine; Tetrazine-NH2
UNSPSC
12352005
Hazard Statement
H302-H319
Target
Biochemical Assay Reagents
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
NCC1=CC=C(C2=NN=CN=N2)C=C1
Molecular Formula
C9H9N5
Molecular Weight
187.20
Precautions
P264-P270-P280-P330-P501
References & Citations
[1]Devaraj NK, et, al. Fast and sensitive pretargeted labeling of cancer cells through a tetrazine/trans-cyclooctene cycloaddition. Angew Chem Int Ed Engl. 2009;48 (38) :7013-6.|[2]Devaraj NK, et, al. Tetrazine-based cycloadditions: application to pretargeted live cell imaging. Bioconjug Chem. 2008 Dec;19 (12) :2297-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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