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Tetraxetan (Standard)

Tetraxetan (Standard) is the analytical standard of Tetraxetan (HY-W053583) . This product is intended for research and analytical applications. Tetraxetan (DOTA) is a macrocyclic chelating agent. Tetraxetan can form stable coordination complexes with a variety of metal ions (e.g., 68Ga, 111In, 177Lu) . Tetraxetan can be conjugated with targeting molecules (e.g., RGD peptide, folic acid) to enable the complex to target specific biomolecules or cells. Tetraxetan can be used for imaging studies of tumors, including melanoma and folate receptor-positive tumors (e.g., cervical cancer) [1][2][3].

Product Specifications

CAS Number

[60239-18-1]

Product Name Alternative

DOTA (Standard)

UNSPSC

12352005

Target

Biochemical Assay Reagents; Radionuclide-Drug Conjugates (RDCs) ; Reference Standards

Related Pathways

Antibody-drug Conjugate/ADC Related; Others

Field of Research

Cancer

Smiles

O=C(O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1

Molecular Formula

C16H28N4O8

Molecular Weight

404.42

References & Citations

[1]Orcutt KD, et al. Biodistribution and clearance of small molecule hapten chelates for pretargeted radioimmunotherapy. Mol Imaging Biol. 2011 Apr;13 (2) :215-21.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Curated Selection

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