Tetraxetan
Tetraxetan (DOTA) is a macrocyclic chelating agent. Tetraxetan can form stable coordination complexes with a variety of metal ions (e.g., 68Ga, 111In, 177Lu) . Tetraxetan can be conjugated with targeting molecules (e.g., RGD peptide, folic acid) to enable the complex to target specific biomolecules or cells. Tetraxetan can be used for imaging studies of tumors, including melanoma and folate receptor-positive tumors (e.g., cervical cancer) [1][2][3].
Product Specifications
CAS Number
60239-18-1
Product Name Alternative
DOTA
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents; Radionuclide-Drug Conjugates (RDCs)
Related Pathways
Antibody-drug Conjugate/ADC Related; Others
Field of Research
Cancer
Purity
99.95
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1
Molecular Formula
C16H28N4O8
Molecular Weight
404.42
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Biochemical Assay Reagents
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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