Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Tetraxetan

Tetraxetan (DOTA) is a macrocyclic chelating agent. Tetraxetan can form stable coordination complexes with a variety of metal ions (e.g., 68Ga, 111In, 177Lu) . Tetraxetan can be conjugated with targeting molecules (e.g., RGD peptide, folic acid) to enable the complex to target specific biomolecules or cells. Tetraxetan can be used for imaging studies of tumors, including melanoma and folate receptor-positive tumors (e.g., cervical cancer) [1][2][3].

Product Specifications

CAS Number

60239-18-1

Product Name Alternative

DOTA

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Biochemical Assay Reagents; Radionuclide-Drug Conjugates (RDCs)

Related Pathways

Antibody-drug Conjugate/ADC Related; Others

Field of Research

Cancer

Purity

99.95

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1

Molecular Formula

C16H28N4O8

Molecular Weight

404.42

Precautions

H302, H315, H319, H335

References & Citations

[1]Orcutt KD, et al. Biodistribution and clearance of small molecule hapten chelates for pretargeted radioimmunotherapy. Mol Imaging Biol. 2011 Apr;13 (2) :215-21. |[2]Decristoforo C, et al. 68Ga- and 111In-labelled DOTA-RGD peptides for imaging of alphavbeta3 integrin expression. Eur J Nucl Med Mol Imaging. 2008 Aug;35 (8) :1507-15. |[3]Müller C, et al. DOTA conjugate with an albumin-binding entity enables the first folic acid-targeted 177Lu-radionuclide tumor therapy in mice. J Nucl Med. 2013 Jan;54 (1) :124-31.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Biochemical Assay Reagents

Clinical Information

Phase 2

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

SCF (KITLG) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI6E5]
TA507211BM 100 µL

SCF (KITLG) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI6E5]

Sign In for Pricing
View Details
Recombinant Histone H3 (phospho S10) Antibody
RC-16339-01 50 μL

Recombinant Histone H3 (phospho S10) Antibody

Sign In for Pricing
View Details
Recombinant Histone H3 (phospho S10) Antibody
RC-16339-02 100 µL

Recombinant Histone H3 (phospho S10) Antibody

Sign In for Pricing
View Details
Recombinant Histone H3 (phospho S10) Antibody
RC-16339-03 1 mL

Recombinant Histone H3 (phospho S10) Antibody

Sign In for Pricing
View Details
Recombinant Rat CLEC4B2/mDCAR1 Protein (His Tag)
PKSR030278 100 µg

Recombinant Rat CLEC4B2/mDCAR1 Protein (His Tag)

Sign In for Pricing
View Details
Bcl-2 (Apoptosis & Follicular Lymphoma Marker) (BCL2/1878R), Biotin conjugate, 0.1mg/mL
BNCB1878-100 1x 100 µL

Bcl-2 (Apoptosis & Follicular Lymphoma Marker) (BCL2/1878R), Biotin conjugate, 0.1mg/mL

Sign In for Pricing
View Details