2-Methylquinazolin-4-ol (Standard)
2-Methylquinazolin-4-ol (Standard) is the analytical standard of 2-Methylquinazolin-4-ol. This product is intended for research and analytical applications. 2-Methylquinazolin-4-ol is a potent competitive poly (ADP-ribose) synthetase inhibitor, with a Ki of 1.1 μM. 2-Methylquinazolin-4-ol mammalian aspartate transcarbamylase (ATCase) inhibitor, with 0.20 mM[1][2].
Product Specifications
CAS Number
1769-24-0
UNSPSC
12352005
Target
PARP; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Others
Field of Research
Others
Smiles
O=C1NC(C)=NC2=C1C=CC=C2
Molecular Formula
C9H8N2O
Molecular Weight
160.18
References & Citations
[1]S Yoshida, et al. Production of 2-methyl-4[3H]-quinazolinone, an inhibitor of poly (ADP-ribose) synthetase, by bacterium. J Antibiot (Tokyo) . 1991 Jan;44 (1) :111-2.|[2]Mahmoud Balbaa, et al. Inhibition of mammalian aspartate transcarbamylase by quinazolinone derivatives. J Enzyme Inhib Med Chem. 2008 Aug;23 (4) :483-92.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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