(2R,3S,4R) -2- (Hydroxymethyl) tetrahydrothiophene-3,4-diol
(2R,3S,4R) -2- (Hydroxymethyl) tetrahydrothiophene-3,4-diol is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[190315-43-6]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Nucleoside Antimetabolite/Analog
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.74
Solubility
H2O : 62.5 mg/mL (ultrasonic)
Smiles
O[C@H]1CS[C@H](CO)[C@H]1O
Molecular Formula
C5H10O3S
Molecular Weight
150.20
Precautions
H315, H319, H320
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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