IPrAgCl
IPrAgCl is an antibacterial agent. IPrAgCl exhibits antiproliferative activity against MCF7 cell line with an IC50 of 30 nM. IPrAgCl has an IC50 of 35 nM against KB cancer cell line. IPrAgCl induces apoptosis in HL60 cell line. IPrAgCl promotes apoptosis-inducing factor translocation from the mitochondrial to the nuclear compartment[1].
Product Specifications
CAS Number
[873297-19-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Cancer; Infection
Purity
97.0
Smiles
Cl[Ag]=C1N(C=CN1C=2C(=CC=CC2C(C)C)C(C)C)C=3C(=CC=CC3C(C)C)C(C)C
Molecular Formula
C27H36AgClN2
Molecular Weight
531.92
Precautions
H302, H315, H319, H335
References & Citations
[1]Eloy L, et al., Anticancer activity of silver-N-heterocyclic carbene complexes: caspase-independent induction of apoptosis via mitochondrial apoptosis-inducing factor (AIF) . ChemMedChem. 2012 May;7 (5) :805-14.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Curated Selection
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